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Glucose-stimulated insulin secretion in pooled islets isolated from 1015-wk old male (n = 9) and female (n = 6) C57BL6/J mice treated with either control, GLP-1RA or GLP-1RA + Tesaglitazar (n = 9/6/6 biologically independent biological replicates) (e) or with control or GLP-1RA/Tesaglitazar (n = 9/6 independent biological replicates) (f) under dynamic glucose concentrations ranging from 2.716 mM at drug concentrations of 3 nM

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Some animal studies have indicated potential benefits in wound healing and tissue repair, though these findings have not been replicated in rigorous human clinical trials

10.1172/JCI990 23